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Displaying drugs 1 - 25 of 1784 in total
RGG0853
RGG0853 is an E1A lipid complex, a repressor gene complexed with a cationic lipid vector.
Investigational
Matched Synonyms: … E1A gene therapy ... tgDCC-E1A gene therapy …
Matched Description: … RGG0853 is an E1A lipid complex, a repressor gene complexed with a cationic lipid vector. …
Matched Description: … RGG0853 is an E1A lipid complex, a repressor gene complexed with a cationic lipid vector. …
GP-100 antigen
GP-100 antigen is under investigation in clinical trial NCT00006385 (Vaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic Melanoma).
Investigational
Matched Synonyms: … Gp100 adenoviral gene therapy …
Matched Description: … Biological Therapy in Treating Patients With Metastatic Melanoma). ... GP-100 antigen is under investigation in clinical trial NCT00006385 (Vaccine Therapy With or Without …
Matched Description: … Biological Therapy in Treating Patients With Metastatic Melanoma). ... GP-100 antigen is under investigation in clinical trial NCT00006385 (Vaccine Therapy With or Without …
Orvacabtagene autoleucel
Investigational
Matched Synonyms: … THERAPY. ... JCARH125 CONSISTS OF HUMAN CULTURE EXPANDED GENETICALLY MODIFIED AUTOLOGOUS T CELLS FOR CELL-BASED GENE …
Betibeglogene autotemcel
Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene (βA-T87Q-globin) to hematopoietic stem cells in order to treat β-thalassemia. β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a significant decrease in the production of β-globin. This affects...
Approved
Investigational
Matched Synonyms: … Autologous CD34+ cells encoding βA-T87Q-Globin gene …
Matched Description: … Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene ... therapy available in the U.S. for the treatment of people with β-thalassemia. ... [L42940] β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a …
Matched Categories: … Autologous Hematopoietic Stem Cell-Based Gene Therapy ... Genetic Therapy …
Matched Description: … Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene ... therapy available in the U.S. for the treatment of people with β-thalassemia. ... [L42940] β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a …
Matched Categories: … Autologous Hematopoietic Stem Cell-Based Gene Therapy ... Genetic Therapy …
Voretigene neparvovec
Voretigene Neparvovec-rzyl (VN-rzyl) is an adeno-associated virus vector-based gene therapy. An adeno-associated virus is a small virus that infects humans and other primates. It is not pathogenic and it causes a very mild immune response. This type of virus is vastly used as vectors for gene therapy because they can...
Approved
Matched Synonyms: … Recombinant adeno-associated virus retinal pigment epithelium gene vector AAV2-hRPE65v2 …
Matched Description: … Voretigene Neparvovec-rzyl (VN-rzyl) is an adeno-associated virus vector-based gene therapy. ... This type of virus is vastly used as vectors for gene therapy because they can infect dividing and quiescent ... When used in genetic therapy, this virus is modified for the elimination of its negligible integrative …
Matched Description: … Voretigene Neparvovec-rzyl (VN-rzyl) is an adeno-associated virus vector-based gene therapy. ... This type of virus is vastly used as vectors for gene therapy because they can infect dividing and quiescent ... When used in genetic therapy, this virus is modified for the elimination of its negligible integrative …
Nadofaragene firadenovec
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon alpha-2b) gene …
Matched Description: … It is the first gene therapy approved by the FDA for the treatment of bladder cancer. ... The localized expression of this gene induces anti-tumor effects. ... [A255111] Nadofaragene firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer …
Matched Categories: … Cellular and Gene Therapy ... Genetic Therapy …
Matched Description: … It is the first gene therapy approved by the FDA for the treatment of bladder cancer. ... The localized expression of this gene induces anti-tumor effects. ... [A255111] Nadofaragene firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer …
Matched Categories: … Cellular and Gene Therapy ... Genetic Therapy …
Atidarsagene autotemcel
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … cells (HSPC) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene …
Matched Description: … Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically ... progenitor cells transduced _ex vivo_ using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene …
Matched Categories: … Autologous Hematopoietic Stem Cell-Based Gene Therapy …
Matched Description: … Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically ... progenitor cells transduced _ex vivo_ using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene …
Matched Categories: … Autologous Hematopoietic Stem Cell-Based Gene Therapy …
Tofersen
Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational
Matched Synonyms: … Antisense Oligonucleotide Inhibitor Of The Expression Of Superoxide Dismutase 1 Gene …
Matched Description: … Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene …
Matched Description: … Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene …
Plantago seed
Platango seeds refer to the seeds collected from various species of plantago trees. It is found in some laxatives for treating occasional constipation and restoring regularity in bowel movements. Its potential benefit in maintaining remission in ulcerative colitis has been studied .
Regardless, this agent is most predominantly used as...
Approved
Investigational
Matched Mixtures name: … Metamucil Therapy for Regularity ... Metamucil Therapy for Regularity ... Metamucil Therapy for Regularity …
Matched Products: … Meijer Fiber Therapy ... Rite Aid Fiber Therapy ... Up and Up Fiber Therapy …
Matched Products: … Meijer Fiber Therapy ... Rite Aid Fiber Therapy ... Up and Up Fiber Therapy …
Eladocagene exuparvovec
Eladocagene exuparvovec is a recombinant adeno-associated virus-2 (AAV2)-based gene therapy that expresses human aromatic L-amino acid decarboxylase (AADC), and it is used to treat AADC deficiency, a fatal and rare genetic disorder that causes severe disability in pediatric patients.[L43642,L43672] Patients with AADC have mutations in the dopa decarboxylase (DDC) gene...
Approved
Investigational
Matched Description: … Eladocagene exuparvovec is a recombinant adeno-associated virus-2 (AAV2)-based gene therapy that expresses ... [A253697,L43672] Before the approval of this gene therapy, the treatment options for patients with AADC ... [L43642,L43672] Patients with AADC have mutations in the dopa decarboxylase (DDC) gene that encodes the …
Matched Categories: … Genetic Therapy …
Matched Categories: … Genetic Therapy …
Lanolin
Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments .
Lanolin is the purified, secreted...
Approved
Matched Products: … LanoGuard Dry Skin Therapy ... Lantiseptic Dry Skin Therapy ... Lantiseptic by Dermarite Dry Skin Therapy …
Lovotibeglogene autotemcel
Lovotibeglogene autotemcel consists of autologous hematopoietic stem and progenitor cells transduced with the BB305 lentiviral vector encoding a modified β-globin gene. Specifically, lovotibeglogene autotemcel provides a functional copy of a modified beta-globin gene (βA-T87Q-globin) that when combined with α-globin, produces hemoglobins with similar oxygen-binding capacity as wild type hemoglobin. Additionally,...
Approved
Investigational
Matched Description: … [L49266] It was approved alongside [exagamglogene autotemcel] (Casgevy), another gene therapy, with the ... stem and progenitor cells transduced with the BB305 lentiviral vector encoding a modified β-globin gene ... Specifically, lovotibeglogene autotemcel provides a functional copy of a modified beta-globin gene (β …
Matched Categories: … Autologous Hematopoietic Stem Cell-Based Gene Therapy ... Genetic Therapy …
Matched Categories: … Autologous Hematopoietic Stem Cell-Based Gene Therapy ... Genetic Therapy …
Donislecel
Donislecel is the first allogeneic pancreatic islet cellular from deceased donor pancreatic cells used for the treatment of adult type 1 diabetes with unsuccessful control of glycated hemoglobin, despite intensive diabetes management and treatments.[L47166,L47196] The primary mechanism of action of donislecel is attributed to the secretion of insulin and other...
Approved
Matched Categories: … Cellular and Gene Therapy …
Coal tar
Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic compounds.
It has been...
Approved
Matched Products: … Advanced Psoriasis Therapy ... Psodex Psoriasis Cream Standard Therapy ... Psodex Psoriasis Cream Intensive Therapy …
Ciltacabtagene autoleucel
Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000, and is variable in its presentation - some patients may remain entirely asymptomatic, while others may experience a range of symptoms including...
Approved
Investigational
Matched Categories: … Antineoplastic cell and gene therapy …
Petrolatum
A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Mixtures name: … Anbesol Cold Sore Therapy ... Vaseline Lip Therapy Spf15 Gel ... Kiss Therapy Medicated Lip Balm …
Matched Products: … Vaseline Lip Therapy Cherry ... Moisture Therapy Ultra Skin Renewal ... Vaseline Lip Therapy Lip Gel …
Matched Products: … Vaseline Lip Therapy Cherry ... Moisture Therapy Ultra Skin Renewal ... Vaseline Lip Therapy Lip Gel …
Onasemnogene abeparvovec
Onasemnogene abeparvovec is an adeno-associated virus vector-based gene therapy that has been approved by the FDA in May 2019 for the treatment of infant patients (less than 2 years of age) with spinal muscular atrophy (SMA) and a specific mutation in the survival motor neuron 1 (SMN1) gene. SMA is...
Approved
Matched Description: … Onasemnogene abeparvovec is an adeno-associated virus vector-based gene therapy that has been approved ... Onasemnogene abeparvovec is the first gene therapy that was approved for this indication in the USA. ... [Nusinersen] is another gene therapy that is currently approved by the FDA for the treatment of SMA in …
Matched Categories: … Cellular and Gene Therapy ... Genetic Therapy …
Matched Categories: … Cellular and Gene Therapy ... Genetic Therapy …
Allantoin
Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Mixtures name: … Cellzyme Secret Therapy ... Anbesol Cold Sore Therapy ... Cellzyme Secret Therapy 3845 …
Matched Products: … Gene 16 Whitening Factor ... Alra Therapy ... Phyton Therapy Cleansing Bar …
Matched Products: … Gene 16 Whitening Factor ... Alra Therapy ... Phyton Therapy Cleansing Bar …
Propylene glycol
A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Approved
Investigational
Matched Mixtures name: … Dry Eye Therapy …
Matched Categories: … Drug Therapy …
Matched Products: … HEB Lubricant Eye Drops Dry Eye Therapy …
Matched Categories: … Drug Therapy …
Matched Products: … HEB Lubricant Eye Drops Dry Eye Therapy …
Benzoyl peroxide
Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Mixtures name: … CVS Advance Acne Therapy Kit ... CVS Advance Acne Therapy Kit ... Complete Acne Therapy System …
Matched Products: … Acne Therapy ... Acne Therapy Cleansing Wash ... SkinPharmacy Advanced Acne Therapy Spot Treatment …
Matched Products: … Acne Therapy ... Acne Therapy Cleansing Wash ... SkinPharmacy Advanced Acne Therapy Spot Treatment …
Salicylic acid
A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Mixtures name: … CVS Advance Acne Therapy Kit ... Neutrogena Complete Acne Therapy System ... SkinPharmacy Advanced Acne Therapy Kit …
Matched Products: … Damoae Therapy Tonic ... Advanced Acne Therapy ... Neriumrx Acne Therapy …
Matched Products: … Damoae Therapy Tonic ... Advanced Acne Therapy ... Neriumrx Acne Therapy …
Alipogene tiparvovec
Alipogene tiparvovec is an adeno-associated viral vector of serotype 1-based gene therapy that delivers the Ser(447)X variant of the human lipoprotein lipase (LPL) gene. It is being investigated for the treatment of lipoprotein lipase (LPL) deficiency.[A259796, A259801, A259806, A259811]
Approved
Investigational
Matched Description: … Alipogene tiparvovec is an adeno-associated viral vector of serotype 1-based gene therapy that delivers ... the Ser(447)X variant of the human lipoprotein lipase (LPL) gene. …
Methyl salicylate
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and...
Approved
Vet approved
Matched Mixtures name: … Therapy Pain ... Pain Therapy ... Ultra Therapy Pain Relief …
Matched Products: … Jason Cooling Minerals and Tea Tree Pain Therapy …
Matched Products: … Jason Cooling Minerals and Tea Tree Pain Therapy …
Displaying drugs 1 - 25 of 1784 in total